Phase 1 Study of Neoadjuvant Short-Course Radiation Therapy Concurrent With Infusional 5-Fluorouracil for the Treatment of Locally Advanced Rectal Cancer

Purpose: To assess the safety and feasibility of neoadjuvant short-course radiation therapy (RT) concurrent with continuous infusion 5-fluorouracil (5-FU) for the treatment of locally advanced rectal cancer.Methods and Materials: Patients with cT3-4 or N + rectal adenocarcinoma based on ultrasound or magnetic resonance imaging were prospectively en

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Assessing the role of dens in the spread, establishment and persistence of sarcoptic mange in an endangered canid

Sarcoptic mange is a skin disease caused by the mite Sarcoptes scabiei that can devastate populations of wild species.S.scabiei can survive off-host and remain infective for specific periods.In den-dwelling species, dislodged mites could be protected from the environmental conditions that impair their survival thus supporting pathogen transmission.

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